Verify that FourPlay.dll is inside Data/F4SE/Plugins/ and not floating in the main Data directory. Missing C++ Redistributables
F4SE Plugin New (F4SE) is a powerful plugin framework for Skyrim that enables developers to create complex mods that interact with the game's code. F4SE provides a range of benefits, including:
the .dll and .ini files from the FourPlay download directly into the Plugins folder. Mod Manager Installation (Recommended) If you use Mod Organizer 2 (MO2) or Vortex :
The modding community experienced a massive shakeup with Bethesda's unexpected Next-Gen updates for Fallout 4. These updates altered the game's executable file, effectively breaking every single F4SE plugin in existence.