Over a career spanning more than two decades, Sneha has starred in over 40 Tamil films, alongside top-tier actors including Kamal Haasan, Vijay, Ajith Kumar, Vikram, Suriya, Dhanush, and Silambarasan.
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| Year | Film Title | Co-Stars | Notes | | :--- | :--- | :--- | :--- | | 2000 | Ennavale | R. Madhavan | Tamil Debut | | 2001 | Aanandham | Mammootty, Abbas | First Commercial Success | | 2002 | Unnai Ninaithu | R. Madhavan | Won Filmfare Best Supporting Actress | | 2002 | April Maadhathil | Srikanth, Venkat Prabhu | | | 2002 | Virumbugiren | Prashanth | Career-defining role | | 2003 | Vaseegara | Vijay | | | 2003 | Parthiban Kanavu | Srikanth | Played a dual role | | 2004 | Vasool Raja MBBS | Kamal Haasan | Cult classic comedy | | 2004 | Autograph | Cheran | Critically acclaimed | | 2005 | Radha Gopalam | Srikanth | | | 2006 | Pudhu Pettai | Dhanush | Won Filmfare Best Actress - Tamil | | 2007 | Naan Avanillai | Jeevan | Blockbuster hit (ran 100+ days) | | 2008 | Pirivom Santhippom | Cheran, Vimal | Won Tamil Nadu State Film Award | | 2011 | Bhavani IPS | M. Sasikumar | | | 2020 | Pattas | Dhanush | Played a powerful mother role | | 2023 | Christopher | Mammootty | Malayalam-Tamil bilingual | | 2024 | The Greatest of All Time | Vijay | Crossover success | | 2025 | Retro | Suriya | Upcoming release | Over a career spanning more than two decades,