Resident Evil 6 Fatal Error Failed Open File -

If the game runs after disabling your AV, add the entire Resident Evil 6 installation folder to your antivirus software's Exclusion List or Whitelist . 4. Install/Update Required Software (DirectX & VCRedist)

Real-time scanning may block or quarantine game files (especially .arc , .dat , or .exe ). resident evil 6 fatal error failed open file